Macbutin Tablet

Description

Macbutin Tablet is an antibiotic, used in the treatment of tuberculosis with HIV (human immunodeficiency virus) infection. It helps to fight germs (bacteria) called mycobacteria, which cannot be destroyed by other antibiotics in people who have a weaker immunity. Macbutin Tablet may be used alone or in combination with other medicines to help prevent serious infections caused by microorganisms like mycobacterium avium complex (MAC). It should be taken in the dose and duration as advised by the doctor. This medicine should be taken on an empty stomach. It is better to take it at the same time each day to get the most benefit and you should keep on taking this medicine for as long as you are prescribed. Stopping it early may make the infection to come back and harder to treat. Some people may develop side effects like decreased white blood cells, anemia, rash, nausea, and fever. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or do not go away. Before starting treatment with this medicine, you should tell your doctor if you are pregnant, breastfeeding, or suffering from any liver, kidney, or heart problems or if you are allergic to any medicine. You may be regularly monitored with blood tests and chest x-rays to check that you do not have active tuberculosis or any other mycobacterial disease. Your doctor may advise for regular eye examination and liver function tests while using it.

Introduction

In Tuberculosis with HIV infection Macbutin Tablet helps treat Mycobacterium avium complex disease (MAC; a bacterial infection that may cause serious symptoms) in patients with human immunodeficiency virus (HIV) infection. It kills as well as stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Benefits

Macbutin Tablet works by inhibiting an enzyme DNA-dependent RNA polymerase in bacteria, leading to the suppression of RNA synthesis that is required for survival and this leads to cell death of infection-causing bacteria. This helps treat Mycobacterium avium complex disease (tuberculosis) in patients with human immunodeficiency virus (HIV) infection.

How to use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Macbutin Tablet is to be taken empty stomach. Avoid Macbutin Tablet with acidic food and beverages such as sugar, certain dairy products, fish, processed foods, fresh meats and processed meats,sodas and other sweetened beverages.

Safety Advice

- Alcohol : CONSULT YOUR DOCTOR - It is not known whether it is safe to consume alcohol with Macbutin Tablet. Please consult your doctor. - Pregnancy : SAFE IF PRESCRIBED - Macbutin Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies. - Breast feeding : SAFE IF PRESCRIBED - Macbutin Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. - Driving : SAFE - Macbutin Tablet does not usually affect your ability to drive. - Kidney : CAUTION - Macbutin Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Macbutin Tablet may be needed. Please consult your doctor. - Liver : CAUTION - Macbutin Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Macbutin Tablet may be needed. Please consult your doctor.